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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5082
|
pubmed:dateCreated |
1992-11-25
|
pubmed:abstractText |
Cancer is the leading cause of death in Japan. Recent changes in cancer incidence patterns may reflect the trend toward a more Western diet and life-style. Among the dietary factors that contribute to carcinogenesis are the heterocyclic amines, a group of mutagenic compounds present in cooked meat and fish. Carcinogenesis is a multistep process in which cells accumulate multiple genetic alterations as they progress to a more malignant phenotype. Recognition of the growing number of interacting factors that contribute to carcinogenesis may force reconsideration of current methods of risk assessment.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0036-8075
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
23
|
pubmed:volume |
258
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
603-7
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:1411570-Amines,
pubmed-meshheading:1411570-Carcinogens,
pubmed-meshheading:1411570-Cocarcinogenesis,
pubmed-meshheading:1411570-Diet,
pubmed-meshheading:1411570-Heterocyclic Compounds,
pubmed-meshheading:1411570-Humans,
pubmed-meshheading:1411570-Japan,
pubmed-meshheading:1411570-Mutagens,
pubmed-meshheading:1411570-Neoplasms
|
pubmed:year |
1992
|
pubmed:articleTitle |
Multistep carcinogenesis: a 1992 perspective.
|
pubmed:affiliation |
National Cancer Center, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|