Linked Life Data

1386693

Source:http://linkedlifedata.com/resource/pubmed/id/1386693

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-9-8
pubmed:abstractText
The studies presented here describe allogeneic reactions in the bicolor damselfish, Pomacentrus partitus, a tropical marine teleost. Damselfish were immunized twice at 2-week intervals either by placement of reciprocal allografts or with primary cultures of epithelial cells. Two weeks after the second immunization, recipient splenocytes were tested for alloreactivity toward donor and third-party pronephros cells. For those animals immunized with cultured cells, reactivity toward donor and third-party epithelial cells was also examined. Unprimed animals responded to allogeneic pronephros between days 8 and 10 (28 degrees C). Fish immunized with epithelial cells showed accelerated mixed leukocyte reactions, with optimal responses occurring between days 4 and 6. Moreover, responses to the immunogen preceded responses to donor pronephros tissue by 2 days, occurring on day 2 or day 4. In addition, primed responses were of significantly greater magnitude than primary reactions. Reactivity toward third-party pronephros tissue paralleled responses of naive animals, indicating the specificity of response. No reactivity toward epithelial cells was observed in the absence of immunization, suggesting that accessory cell functions of damselfish pronephros and epithelial cells differ.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
313-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Primed allogeneic reactions to leukocytes and epithelial cells in the bicolor damselfish.
pubmed:affiliation
Department of Microbiology and Immunology, School of Medicine, University of Miami, Florida 33101.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.