Linked Life Data

13844851

Source:http://linkedlifedata.com/resource/pubmed/id/13844851

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1960-12-1
pubmed:abstractText
Induction of hepatic amoebiasis with two strains of Entamoeba histolytica has been attempted by direct inoculation of trophozoites into the livers of rats, hamsters, and guinea-pigs, and by intravenous injection into guinea-pigs. A high incidence of amoebic abscesses was obtained in hamsters. Rats and guinea-pigs were relatively less susceptible. The two strains of Entamoeba histolytica differed in virulence. Serial liver passage increased their virulence for the hamster liver, and also increased invasiveness to the rat caecum. The chemotherapeutic effects of chloroquine, emetine, and some anilides were determined. The procedure finally adopted was based on mean survival times of treated and untreated animals. Chloroquine and emetine were effective under conditions which greatly favoured the drugs, but the anilides showed little effect.
pubmed:commentsCorrections
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
OM
pubmed:status
OLDMEDLINE
pubmed:month
Dec
pubmed:issn
0366-0826
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
488-92
pubmed:dateRevised
2010-9-21
pubmed:year
1959
pubmed:articleTitle
Experimental hepatic amoebiasis and its application to chemotherapeutic studies.
pubmed:publicationType
Journal Article