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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1992-11-12
|
| pubmed:abstractText |
A number of nucleotide phosphoramidites are now available that permit the chemical synthesis of RNA, modified RNA and RNA-DNA chimeric oligonucleotides. Since the chemical strategy allows the introduction of a particular modification at any given site in a nucleotide polymer, very subtle and specific questions regarding structure-function relationships in RNA may be addressed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0968-0004
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
334-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1384179-Base Sequence,
pubmed-meshheading:1384179-Chimera,
pubmed-meshheading:1384179-DNA,
pubmed-meshheading:1384179-Molecular Sequence Data,
pubmed-meshheading:1384179-Mutagenesis, Site-Directed,
pubmed-meshheading:1384179-RNA,
pubmed-meshheading:1384179-Structure-Activity Relationship
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Exploiting the chemical synthesis of RNA.
|
| pubmed:affiliation |
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
|
| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|