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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-11-4
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pubmed:abstractText |
The developmental expression of voltage-sensitive K+ channels was analyzed by Northern blot in mouse skeletal muscle. Of nine Shaker-like genes studied, eight are expressed in this mammalian muscle. Their expression is differentially regulated during development. The mouse cell line C2C12 has been used to study expression of voltage-sensitive K+ channels during in vitro myotube differentiation. Different voltage-sensitive K+ channel messages are also expressed in these cells which display a pattern of expression depending upon the differentiation stage. The message for the very peculiar K+ channel of IsK type could only be detected by polymerase chain reaction on skeletal muscle mRNA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
310
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
162-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1383027-Animals,
pubmed-meshheading:1383027-Blotting, Northern,
pubmed-meshheading:1383027-Brain,
pubmed-meshheading:1383027-Cell Differentiation,
pubmed-meshheading:1383027-Cells, Cultured,
pubmed-meshheading:1383027-DNA,
pubmed-meshheading:1383027-DNA Probes,
pubmed-meshheading:1383027-Mice,
pubmed-meshheading:1383027-Muscle Development,
pubmed-meshheading:1383027-Muscles,
pubmed-meshheading:1383027-Polymerase Chain Reaction,
pubmed-meshheading:1383027-Potassium Channels,
pubmed-meshheading:1383027-RNA
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pubmed:year |
1992
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pubmed:articleTitle |
Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.
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pubmed:affiliation |
Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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