Linked Life Data

1380866

Source:http://linkedlifedata.com/resource/pubmed/id/1380866

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1992-9-25
pubmed:abstractText
Dye coupling among glial cells in the ganglia of the myenteric and submucosal plexuses of the guinea-pig ileum was studied by intracellular injection of the dye Lucifer yellow (LY), which crosses gap junctions. The injection of a single glial cell with LY resulted in the staining of many glia. The mean number of cells coupled to the injected one was 87.0 +/- 7.9 in the myenteric plexus, and 20.7 +/- 5.6 in the submucosal plexus. As previously shown for myenteric plexus, injection of horseradish peroxidase into submucosal glia resulted in the staining of only a single cell. Dye coupling was significantly reduced in both plexuses by lowering intracellular pH, by replacing 100 mM of the chloride ions with propionate ions or by bubbling the solution with 100% CO2. Octanol (0.3 mM) also markedly diminished dye coupling in the two preparations. These treatments are known to block gap junctions in a variety of tissues. It is concluded that, like central glial cells, enteric glia are extensively coupled. This coupling is apparently mediated by gap junctions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
578
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
94-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Modulation of dye coupling among glial cells in the myenteric and submucosal plexuses of the guinea pig.
pubmed:affiliation
Laboratory of Experimental Surgery, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't