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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-9-18
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pubmed:abstractText |
Vasopeptidase inhibitors are a new class of compounds that inhibit both angiotensin-converting enzyme (ACE) and neutral endopeptidase. This study determined whether treatment with the vasopeptidase inhibitor omapatrilat (OMA) produced different effects on renal and cardiovascular structure compared with inhibition of ACE by enalapril (ENP) in rats with two-kidney, one clip hypertension (2K1C).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0931-0509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2005-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:13679474-Analysis of Variance,
pubmed-meshheading:13679474-Animals,
pubmed-meshheading:13679474-Biopsy, Needle,
pubmed-meshheading:13679474-Blotting, Western,
pubmed-meshheading:13679474-Disease Models, Animal,
pubmed-meshheading:13679474-Enalapril,
pubmed-meshheading:13679474-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:13679474-Hypertension, Renal,
pubmed-meshheading:13679474-Immunohistochemistry,
pubmed-meshheading:13679474-Male,
pubmed-meshheading:13679474-Organ Size,
pubmed-meshheading:13679474-Probability,
pubmed-meshheading:13679474-Protease Inhibitors,
pubmed-meshheading:13679474-Pyridines,
pubmed-meshheading:13679474-Random Allocation,
pubmed-meshheading:13679474-Rats,
pubmed-meshheading:13679474-Rats, Inbred Strains,
pubmed-meshheading:13679474-Reference Values,
pubmed-meshheading:13679474-Renal Circulation,
pubmed-meshheading:13679474-Survival Rate,
pubmed-meshheading:13679474-Thiazepines
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pubmed:year |
2003
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pubmed:articleTitle |
Beneficial and adverse renal and vascular effects of the vasopeptidase inhibitor omapatrilat in renovascular hypertensive rats.
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pubmed:affiliation |
University Hospital of Hamburg-Eppendorf, Department of Medicine, Division of Nephrology, Pav. 61, Martinistrasse 52, D-20246 Hamburg, Germany. wenzel@uke.uni-hamburg.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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