Linked Life Data

13679008

Source:http://linkedlifedata.com/resource/pubmed/id/13679008

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-9-18
pubmed:abstractText
Direct ingestion of the infectious BSE agent via meat and bone meal (MBM) is commonly regarded as the main route of infection for cattle. I propose that another plausible route of infection has been overlooked so far, namely the ingestion of MBM by mother animals who susequently pass on the infectious agent in their colostrum and thus infect their offspring. This theory could explain why, although infection is thought to occur at very early stages in life, many BSE animals had not received MBM containing feeds when calves. Literature evidence on intact protein absorption in adult mammals, on the presence of the infectious BSE agent in the blood in the pre-symptomatic stage, and on the incorporation of intact dietary protein into colostrum or milk in humans and pigs, support this hypothesis. This hypothesis does not necessarily mean that colostrum or milk from BSE-positive animals is infectious. Rather, the mother animals in the hypothesis scenario will be themselves infected, but probably not develop the disease due to its long incubation period, thus occurring in statistics as 'negative' animals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0306-9877
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-43
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Do cows fed BSE-infected meat and bone meal in the colostrum-producing stage pass on infectious BSE agent to their calves?
pubmed:affiliation
Institute of Animal Physiology, Physiological Chemistry and Animal Nutrition, Veterinary Faculty of the Ludwigs-Maximilians-University of Munich, Veterinaerstr. 13, 80539, Munich, Germany. clauss@tiph.vetmed.uni-muenchen.de
pubmed:publicationType
Journal Article