Linked Life Data

1348494

Source:http://linkedlifedata.com/resource/pubmed/id/1348494

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-5-13
pubmed:abstractText
Tum- comprises a class of genes, mutation of which in P815 tumor cells has led to the acquisition of new cytotoxic T cell-recognized epitopes. The cells carrying the mutant alleles have impaired tumorigenicity compared with their progenitors due to in vivo induction of a cytotoxic T-cell response specific for tum- antigens. Two tum- genes, P91A and P35B, were found to be single copy loci mapping to chromosomes 11 and 15 respectively. A third, P198, was found to map to chromosome 7 and to be a member of a small gene family with other members on chromosomes 13, 14, and 15. Multiple P198-related sequences were found in other mammalian species suggesting the P198 related gene family is a general feature of mammalian genomes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0093-7711
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:geneSymbol
As-1, Es-10For-5, Hox-2, Krt-1, Lth-1, Myla, Ngfg, P198, P198-13, P198-14, P198-7, P35B, P91A, Rasa, TJ-2.7, Tam-1, Xmv-13, Xmv-30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-23
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198.
pubmed:affiliation
Clinical Research Centre, Harrow, Middlesex, UK.
pubmed:publicationType
Journal Article