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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1993-2-26
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pubmed:abstractText |
This report concerns 296 children (67% males and 33% females) from 24 countries who started renal replacement therapy (RRT) for end-stage renal failure between 1969 and 1988. Children under 2 years of age represented 3.6%, 4.4%, and 8.9% of all children under 15 years of age who started RRT in 1978-1982, 1983-1985, and 1986-1988 respectively. During the first 2 years of life, the most frequent causes of end-stage renal failure were renal hypoplasia and dysplasia (24%), and haemolytic-uraemic syndrome (17%). During 1986-1988 the initial therapy for ESRF was continuous ambulatory peritoneal dialysis (CAPD) in 60%, haemodialysis 25%, intermittent peritoneal dialysis 8%, and 7% were transplanted without prior dialysis. Between 1978 and 1988, 139 of these children were grafted; 53 received a graft (39 cadaveric, 10 living donor, 4 donor uncertain) below, and 86 (71 cadaveric, 14 living donor, 1 donor uncertain) above 2 years of age. One-year graft survival was 54% in the 53 children grafted below 2 years of age and 65% in the 86 grafted above 2 years of age. Only two of the 24 living donor grafts were lost during the first year after grafting. These results compare favourably with the 67% 1-year graft survival of all 278 children aged 2 to less than 6 years at grafting in 1978-1988 on the Registry's file. The 3-year survival of all children aged less than 2 years at start of RRT was 65% in 1978-1982 and rose to 78% in 1986-1988. Twenty-three percent of all deaths were caused by infections.(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0931-0509
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1171-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1337155-Female,
pubmed-meshheading:1337155-Graft Survival,
pubmed-meshheading:1337155-Humans,
pubmed-meshheading:1337155-Infant,
pubmed-meshheading:1337155-Infant, Newborn,
pubmed-meshheading:1337155-Kidney Failure, Chronic,
pubmed-meshheading:1337155-Kidney Transplantation,
pubmed-meshheading:1337155-Male,
pubmed-meshheading:1337155-Peritoneal Dialysis,
pubmed-meshheading:1337155-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:1337155-Registries,
pubmed-meshheading:1337155-Renal Dialysis,
pubmed-meshheading:1337155-Survival Rate
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pubmed:year |
1992
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pubmed:articleTitle |
Renal replacement therapy for end-stage renal failure before 2 years of age.
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pubmed:affiliation |
Medizinische Hochschule, Hannover, Germany.
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pubmed:publicationType |
Journal Article
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