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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-1-13
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pubmed:abstractText |
Within 2 days neurotensin (NT) and ACTH administrations markedly enhanced the average volume of zona glomerulosa (ZG) cells and plasma aldosterone concentration (PAC) in intact rats. In dexamethasone-treated rats, both NT and ACTH evoked a clearcut ZG-cell hypertrophy, but only NT was able to raise PAC. In conclusion, our findings indicate that NT is a potent stimulator of the growth and secretion of rat ZG in vivo, and suggest that the mechanism underlying this action of NT does not involve the well-known NT-induced stimulation of ACTH release.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0258-851X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
523-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1333833-Adrenocorticotropic Hormone,
pubmed-meshheading:1333833-Aldosterone,
pubmed-meshheading:1333833-Animals,
pubmed-meshheading:1333833-Cell Size,
pubmed-meshheading:1333833-Dexamethasone,
pubmed-meshheading:1333833-Female,
pubmed-meshheading:1333833-Hypertrophy,
pubmed-meshheading:1333833-Neurotensin,
pubmed-meshheading:1333833-Rats,
pubmed-meshheading:1333833-Rats, Wistar,
pubmed-meshheading:1333833-Secretory Rate,
pubmed-meshheading:1333833-Stimulation, Chemical,
pubmed-meshheading:1333833-Zona Glomerulosa
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pubmed:articleTitle |
Neurotensin stimulates the growth and secretion of rat adrenal zona glomerulosa.
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pubmed:affiliation |
Department of Histology and Embryology, University School of Medical Sciences, Poznan, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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