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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1992-12-1
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pubmed:databankReference | |
pubmed:abstractText |
Two members of the human ubiquitin gene subfamily encoding ubiquitin fused to a 52-residue ribosomal protein (UbA52) were cloned, sequenced, and analyzed. Both were found to be processed (reverse-transcribed) pseudogenes, containing several nucleotide substitutions and deletions that severely disrupt their potential open-reading frames. Genomic hybridization analysis using probes derived from a functional UbA52 gene (UBA52) suggests that the UbA52 subfamily consists of one intron-containing, transcriptionally active gene and approximately eight processed pseudogenes, a feature characteristic of mammalian ribosomal protein gene families.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
520-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1330885-Base Sequence,
pubmed-meshheading:1330885-Cloning, Molecular,
pubmed-meshheading:1330885-DNA,
pubmed-meshheading:1330885-Humans,
pubmed-meshheading:1330885-Molecular Sequence Data,
pubmed-meshheading:1330885-Nucleic Acid Hybridization,
pubmed-meshheading:1330885-Pseudogenes,
pubmed-meshheading:1330885-Ribosomal Proteins,
pubmed-meshheading:1330885-Transcription, Genetic,
pubmed-meshheading:1330885-Ubiquitins
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pubmed:year |
1992
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pubmed:articleTitle |
The human ubiquitin/52-residue ribosomal protein fusion gene subfamily (UbA52) is composed primarily of processed pseudogenes.
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pubmed:affiliation |
Division of Clinical Sciences, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|