Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-8-4
pubmed:abstractText
Animal inhalation exposures to fibrous materials such as crocidolite and erionite produce lesions similar to those found in exposed humans. This indicates that the animal inhalation model is relevant for identifying hazardous fibrous materials. Intratracheal instillations and intracoelomic injections are alternative bioassays that can be used to screen for the most biologically active materials. These nonphysiological routes of administration can give false positive results; therefore, animal inhalation studies should be the ultimate bioassay used in the absence of appropriate epidemiological data.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-7742
pubmed:author
pubmed:issnType
Print
pubmed:volume
374
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-36
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The utility of animal inhalation studies to assess the risk of mineral fiber-induced pulmonary cancer.
pubmed:affiliation
Molecular and Cellular Toxicology Group, Inhalation Toxicology Research Institute, Albuquerque, NM 87185.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review