Linked Life Data

1319715

Source:http://linkedlifedata.com/resource/pubmed/id/1319715

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-7-31
pubmed:abstractText
Sexually dimorphic traits were studied in offspring of rats injected with 33 micrograms rat beta-endorphin (beta-END) three times daily from Day 14 to Day 21 of pregnancy. beta-END males had shorter neonatal anogenital distances than did controls and were more likely to show the female lordosis pattern as adults, but they did not differ in male copulatory behavior. When given a choice between spending time with an estrous female or a male, beta-END males showed a lower preference for the female than did control males. The number and somal size of neurons in the bulbocavernosus and dorsolateral nucleus of the lumbar spinal cord were unaffected by drug exposure. Elevated beta-END during fetal ontogeny apparently alters the differentiation of some, but not all, sexually dimorphic traits. The data suggest that endogenous opioids may contribute to the etiology of the prenatal stress syndrome.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0735-7044
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
555-62
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Prenatal beta-endorphin can modulate some aspects of sexual differentiation in rats.
pubmed:affiliation
Villanova University, Pennsylvania 19085.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S.