Linked Life Data

1318038

Source:http://linkedlifedata.com/resource/pubmed/id/1318038

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-7-9
pubmed:databankReference
pubmed:abstractText
We report here, using the androgen-dependent SC2G cell line derived from Shionogi mouse mammary carcinoma SC115, that cDNA encoding mouse homologue of the rat schwannoma-derived growth factor (SDGF) was isolated and its protein product was identified to be an autocrine growth factor which is expressed in response to androgen in this hormone-dependent cell line. The androgen-independent SC1G cells derived from SC115 were shown to express SDGF even in the absence of androgen, while Northern analysis probed with mouse mammary tumor virus (MMTV) DNA showed that the androgen inducible transcriptional machinery remains functional in this hormone independent cell line.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
185
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed-meshheading:1318038-Amino Acid Sequence, pubmed-meshheading:1318038-Androgens, pubmed-meshheading:1318038-Animals, pubmed-meshheading:1318038-Base Sequence, pubmed-meshheading:1318038-Cell Division, pubmed-meshheading:1318038-Glycoproteins, pubmed-meshheading:1318038-Growth Substances, pubmed-meshheading:1318038-Intercellular Signaling Peptides and Proteins, pubmed-meshheading:1318038-Mammary Neoplasms, Experimental, pubmed-meshheading:1318038-Mammary Tumor Virus, Mouse, pubmed-meshheading:1318038-Mice, pubmed-meshheading:1318038-Mitogens, pubmed-meshheading:1318038-Molecular Sequence Data, pubmed-meshheading:1318038-RNA, Messenger, pubmed-meshheading:1318038-Sequence Homology, Nucleic Acid, pubmed-meshheading:1318038-Transcription, Genetic, pubmed-meshheading:1318038-Tumor Cells, Cultured
pubmed:year
1992
pubmed:articleTitle
Androgen-responsive expression and mitogenic activity of schwannoma-derived growth factor on an androgen-dependent Shionogi mouse mammary carcinoma cell line.
pubmed:affiliation
Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
pubmed:publicationType
Journal Article