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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-6-4
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pubmed:abstractText |
To assess whether the hepatitis C virus plays an important role in Chinese patients with acute and chronic liver disease, antibodies to HCV (anti-HCV) were measured by enzyme immunoassay in 67 patients with type A and B acute viral hepatitis, 165 patients with non-A, non-B (NANB) hepatitis, 438 patients with chronic hepatitis, 200 patients with postnecrotic liver cirrhosis, 72 patients with alcoholic liver disease, 55 patients with non-alcoholic fatty liver, 24 patients with toxic and drug-induced hepatitis, and 20 patients with other chronic liver diseases. Anti-HCV was not detected in sera from patients with type A and B acute viral hepatitis, toxic and drug-induced hepatitis, primary biliary cirrhosis, Wilson's disease, or lupoid hepatitis. The anti-HCV prevalence was found to be highest in patients with NANB hepatitis (59% in sporadic and 73.2% in transfusion-associated), 16.4% in non-alcoholic fatty liver, 5.6% in alcoholic liver disease, 6.8% in chronic hepatitis, and 16% in postnecrotic liver cirrhosis. In patients with chronic hepatitis, the anti-HCV prevalence was significantly higher in HBsAg-negative (15/34, 44.1%) than in HBsAg-positive cases (15/404, 3.7%; P less than 0.0001). The results indicate that HCV is a major agent of NANB hepatitis and plays an important role in HBsAg-negative chronic liver disease in Taiwan.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0815-9319
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1315164-Acute Disease,
pubmed-meshheading:1315164-Adolescent,
pubmed-meshheading:1315164-Adult,
pubmed-meshheading:1315164-Aged,
pubmed-meshheading:1315164-China,
pubmed-meshheading:1315164-Chronic Disease,
pubmed-meshheading:1315164-Hepacivirus,
pubmed-meshheading:1315164-Hepatitis Antibodies,
pubmed-meshheading:1315164-Hepatitis C,
pubmed-meshheading:1315164-Humans,
pubmed-meshheading:1315164-Liver Diseases,
pubmed-meshheading:1315164-Middle Aged,
pubmed-meshheading:1315164-Prevalence,
pubmed-meshheading:1315164-Seroepidemiologic Studies
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pubmed:articleTitle |
Prevalence of anti-HCV among Chinese patients with acute and chronic liver disease.
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pubmed:affiliation |
Department of Medicine, Veterans General Hospital, Taipei, Taiwan, ROC.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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