Linked Life Data

1299132

Source:http://linkedlifedata.com/resource/pubmed/id/1299132

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1993-5-12
pubmed:abstractText
The effect of serotonin, Met- and Leu-enkephalin was studied on the dialysed neurons of Helix pomatia L. Both the Ca- and K-currents were modulated by the above agents. Two types of neurons could be distinguished by their response to serotonin in the case of the voltage activated Ca-current. One group responded by increasing the inward Ca-current, others by decreasing it. Met-enkephalin decreased the Ca-current on every studied neuron, while Leu-enkephalin had modulatory action to both directions. Opiate peptides and serotonin showed a dose-dependent effect, but had different threshold concentrations. The peptides and serotonin also influenced the voltage activated transient and delayed K-currents. Serotonin increased the K-current, while Met-enkephalin decreased it, and Leu-enkephalin could either decrease or increase it. The variations on the response to serotonin and the opiate peptides on non-identified dialysed neurons of Helix can be explained by the presence of different receptors on the neurons used.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0236-5383
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-77
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Effect of serotonin and opiate peptides on ion-currents of dialysed Helix neurons.
pubmed:affiliation
Balaton Limnological Research Institute, Academy of Sciences, Tihany, Hungary.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't