Linked Life Data

12962690

Source:http://linkedlifedata.com/resource/pubmed/id/12962690

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-9-9
pubmed:abstractText
Precise regulation of hepatic and peripheral glucose uptake is essential to preserve glucose homeostasis. The liver extracts approximately 1/3 of an oral glucose load, skeletal muscle extracts approximately 1/3, and other tissues, particularly the central nervous system and the formed elements of the blood, take up the balance. The load of glucose reaching the liver, the insulin concentration, and the route of glucose delivery (the hepatic portal or a peripheral vein) are key determinants of the rate of net hepatic glucose uptake. Glucose uptake by muscle requires three steps: delivery of glucose from the blood to the muscle, transport of glucose across the muscle membrane, and phosphorylation of glucose, processes affected by glycaemia and insulinaemia. Exercise stimulates insulin-dependent and -independent muscle glucose uptake, as well as the liver's ability to take up glucose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1521-690X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-64
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Regulation of hepatic and peripheral glucose disposal.
pubmed:affiliation
Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 702 Light Hall, Nashville, TN 37232-0615, USA .
pubmed:publicationType
Journal Article, Review