12960109

Source:http://linkedlifedata.com/resource/pubmed/id/12960109

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017431, umls-concept:C0031327, umls-concept:C0123931, umls-concept:C0681842, umls-concept:C0936012, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	9
pubmed:dateCreated	2003-9-8
pubmed:abstractText	The purpose was to explore the relationships between irinotecan disposition and allelic variants of genes coding for adenosine triphosphate binding cassette transporters and enzymes of putative relevance for irinotecan.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/U01 GM63340
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/ABCG2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin, http://linkedlifedata.com/resource/pubmed/chemical/Carboxylesterase, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Glucuronic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Glucuronosyltransferase, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Multidrug Resistance-Associated..., http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein, http://linkedlifedata.com/resource/pubmed/chemical/X-ray repair cross complementing..., http://linkedlifedata.com/resource/pubmed/chemical/bilirubin..., http://linkedlifedata.com/resource/pubmed/chemical/irinotecan, http://linkedlifedata.com/resource/pubmed/chemical/multidrug resistance-associated..., http://linkedlifedata.com/resource/pubmed/chemical/multidrug resistance-associated...
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1078-0432
pubmed:author	pubmed-author:BakerSharyn DSD, pubmed-author:KarlssonMats OMO, pubmed-author:MarshSharonS, pubmed-author:MathijssenRon H JRH, pubmed-author:McLeodHoward LHL, pubmed-author:SparreboomAlexA, pubmed-author:VerweijJaapJ, pubmed-author:XieRujiaR
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	3246-53
pubmed:dateRevised	2008-11-21
pubmed:meshHeading	pubmed-meshheading:12960109-ATP-Binding Cassette Transporters, pubmed-meshheading:12960109-Adenosine Triphosphate, pubmed-meshheading:12960109-Adult, pubmed-meshheading:12960109-Aged, pubmed-meshheading:12960109-Alleles, pubmed-meshheading:12960109-Camptothecin, pubmed-meshheading:12960109-Carboxylesterase, pubmed-meshheading:12960109-Cell Line, Tumor, pubmed-meshheading:12960109-Cytochrome P-450 CYP3A, pubmed-meshheading:12960109-Cytochrome P-450 Enzyme System, pubmed-meshheading:12960109-DNA-Binding Proteins, pubmed-meshheading:12960109-Female, pubmed-meshheading:12960109-Gene Frequency, pubmed-meshheading:12960109-Genotype, pubmed-meshheading:12960109-Glucuronic Acids, pubmed-meshheading:12960109-Glucuronosyltransferase, pubmed-meshheading:12960109-Homozygote, pubmed-meshheading:12960109-Humans, pubmed-meshheading:12960109-Male, pubmed-meshheading:12960109-Membrane Transport Proteins, pubmed-meshheading:12960109-Middle Aged, pubmed-meshheading:12960109-Models, Biological, pubmed-meshheading:12960109-Multidrug Resistance-Associated Proteins, pubmed-meshheading:12960109-Neoplasm Proteins, pubmed-meshheading:12960109-P-Glycoprotein, pubmed-meshheading:12960109-Phenotype, pubmed-meshheading:12960109-Polymorphism, Genetic, pubmed-meshheading:12960109-Protein Binding
pubmed:year	2003
pubmed:articleTitle	Irinotecan pathway genotype analysis to predict pharmacokinetics.
pubmed:affiliation	Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, 3075 EA Rotterdam, the Netherlands.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S.