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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-9-4
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pubmed:abstractText |
The gut hormone fragment peptide YY3-36 (PYY) reduces appetite and food intake when infused into subjects of normal weight. In common with the adipocyte hormone leptin, PYY reduces food intake by modulating appetite circuits in the hypothalamus. However, in obesity there is a marked resistance to the action of leptin, which greatly limits its therapeutic effectiveness. We investigated whether obese subjects were also resistant to the anorectic effects of PYY.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1533-4406
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 Massachusetts Medical Society
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pubmed:issnType |
Electronic
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pubmed:day |
4
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pubmed:volume |
349
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
941-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12954742-Appetite,
pubmed-meshheading:12954742-Cross-Over Studies,
pubmed-meshheading:12954742-Double-Blind Method,
pubmed-meshheading:12954742-Eating,
pubmed-meshheading:12954742-Female,
pubmed-meshheading:12954742-Ghrelin,
pubmed-meshheading:12954742-Humans,
pubmed-meshheading:12954742-Insulin,
pubmed-meshheading:12954742-Leptin,
pubmed-meshheading:12954742-Male,
pubmed-meshheading:12954742-Obesity,
pubmed-meshheading:12954742-Peptide Hormones,
pubmed-meshheading:12954742-Peptide YY
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pubmed:year |
2003
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pubmed:articleTitle |
Inhibition of food intake in obese subjects by peptide YY3-36.
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pubmed:affiliation |
Department of Metabolic Medicine, Imperial College Faculty of Medicine at Hammersmith Campus, Du Cane Rd., London W12 0NN, United Kingdom.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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