Source:http://linkedlifedata.com/resource/pubmed/id/12953798
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-9-4
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pubmed:abstractText |
The presence of a significant amount of 9,11-conjugated linoleic acid (CLA, 9,11-18:2) was confirmed in the liver and plasma lipids of rats fed a 1% (w/w % of diet) eleostearic acid (ESA, 9,11,13-18:3) diet for 4 wk. The chemical structure of the 9,11-CLA apparent in the tissue lipids was identified by gas chromatography-electron impact mass spectrometry after its conversion to a 4,4-dimethyloxazoline derivative. The concentration of CLA in the total fatty acids of the liver and plasma lipids reached to about 1%, for each in the CLA-supplemented rats, while reaching 3.2% and 2.5%, respectively, in the ESA-supplemented rats. The results suggest that alpha-ESA is metabolized partially to CLA via a delta 13-saturation reaction in the rat. Some biological activities observed in alpha-ESA-fed animals may be ascribed also to CLA that is formed from ESA in the body.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4,4-dimethyloxazoline,
http://linkedlifedata.com/resource/pubmed/chemical/9,11-linoleic acid,
http://linkedlifedata.com/resource/pubmed/chemical/Linoleic Acids, Conjugated,
http://linkedlifedata.com/resource/pubmed/chemical/Linolenic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Oxazoles,
http://linkedlifedata.com/resource/pubmed/chemical/eleostearic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0301-4800
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-200
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12953798-Animals,
pubmed-meshheading:12953798-Chromatography, Gas,
pubmed-meshheading:12953798-Linoleic Acids, Conjugated,
pubmed-meshheading:12953798-Linolenic Acids,
pubmed-meshheading:12953798-Liver,
pubmed-meshheading:12953798-Male,
pubmed-meshheading:12953798-Mass Spectrometry,
pubmed-meshheading:12953798-Oxazoles,
pubmed-meshheading:12953798-Rats,
pubmed-meshheading:12953798-Rats, Sprague-Dawley
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pubmed:year |
2003
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pubmed:articleTitle |
The metabolic conversion of 9,11,13-eleostearic acid (18:3) to 9,11-conjugated linoleic acid (18:2) in the rat.
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pubmed:affiliation |
Laboratory of Food & Biodynamic Chemistry, Graduate School of Life Science and Agriculture, Tohoku University, Sendai 981-8555, Japan.
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pubmed:publicationType |
Journal Article
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