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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1993-4-8
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pubmed:abstractText |
An experimental model of clostridial gas gangrene was developed in rats and the therapeutic value of surgical debridement alone versus a combination of surgery and hyperbaric oxygen (HBO) was assessed. The infection was produced by an intramuscular injection of Clostridium perfringens microorganisms. The mortality of untreated rats was 100%. The mortality of the rats treated only with surgery was 37.5% compared to 12.5% when HBO was added to the treatment protocol (p < 0.01). In the group treated with HBO and surgery 82.5% of the animals healed completely and were able to walk normally, whereas the corresponding figure in the rats treated with surgery alone was 12.5% (p < 0.001). In the present experimental setting HBO treatment was an important therapeutic adjunct to surgery reducing both mortality and morbidity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-312X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
356-62
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1292939-Animals,
pubmed-meshheading:1292939-Disease Models, Animal,
pubmed-meshheading:1292939-Evaluation Studies as Topic,
pubmed-meshheading:1292939-Female,
pubmed-meshheading:1292939-Gas Gangrene,
pubmed-meshheading:1292939-Hyperbaric Oxygenation,
pubmed-meshheading:1292939-Rats,
pubmed-meshheading:1292939-Rats, Sprague-Dawley,
pubmed-meshheading:1292939-Wound Healing
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pubmed:year |
1992
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pubmed:articleTitle |
Effect of hyperbaric oxygen and surgery on experimental gas gangrene.
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pubmed:affiliation |
Department of Surgery, University of Turku, Finland.
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pubmed:publicationType |
Journal Article,
Comparative Study
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