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pubmed:abstractText |
ACE inhibitors, when used as monotherapy, are frequently unable to adequately control blood pressure in diabetic patients. A diuretic may be added; however, thiazide diuretics, but not indapamide, have been associated with adverse metabolic effects. Whether these effects also apply to thiazides when administered in the currently used lower doses, and whether they differ from indapamide in their metabolic effects, particularly when used in combination with an ACE inhibitor in diabetic patients, has not been previously studied.
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pubmed:affiliation |
National Health & Medical Research Council of Australia Centre of Clinical Research Excellence in Therapeutics, Department of Epidemiology & Preventive Medicine, Monash University/Alfred Hospital, Prahran, Victoria, Australia. henry.krum@med.monash.edu.au
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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