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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2003-8-18
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pubmed:abstractText |
Bradykinin exerts cardioprotective effects through bradykinin type-2 receptors (BK-2Rs). After acute myocardial infarction in rat, the heart adapts by increasing its number of BK-2Rs. However, in human chronic end-stage heart failure, the number of BK-2Rs is significantly decreased. Thus, the presence of a cardioprotective BK-2R signaling system may be critical in the prevention of pressure overload-induced heart failure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0263-6352
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pubmed:author |
pubmed-author:KaajaRistoR,
pubmed-author:KokkonenJorma OJO,
pubmed-author:KovanenPetri TPT,
pubmed-author:KuoppalaAnttiA,
pubmed-author:LeskinenHanna KHK,
pubmed-author:LiesmaaInkaI,
pubmed-author:LindstedtKen AKA,
pubmed-author:LuodonpääMarjaM,
pubmed-author:RuskoahoHeikkiH,
pubmed-author:RysäJaanaJ,
pubmed-author:ShiotaNaotakaN
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1729-36
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12923406-Angiotensin II,
pubmed-meshheading:12923406-Animals,
pubmed-meshheading:12923406-Aorta,
pubmed-meshheading:12923406-Blood Pressure,
pubmed-meshheading:12923406-Disease Models, Animal,
pubmed-meshheading:12923406-Echocardiography,
pubmed-meshheading:12923406-Fibrosis,
pubmed-meshheading:12923406-Gene Expression,
pubmed-meshheading:12923406-Heart Failure,
pubmed-meshheading:12923406-Hypertrophy, Left Ventricular,
pubmed-meshheading:12923406-Male,
pubmed-meshheading:12923406-RNA, Messenger,
pubmed-meshheading:12923406-Rats,
pubmed-meshheading:12923406-Rats, Inbred SHR,
pubmed-meshheading:12923406-Rats, Inbred WKY,
pubmed-meshheading:12923406-Receptor, Bradykinin B2,
pubmed-meshheading:12923406-Receptors, Bradykinin,
pubmed-meshheading:12923406-Vasoconstrictor Agents
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pubmed:year |
2003
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pubmed:articleTitle |
Expression of bradykinin receptors in the left ventricles of rats with pressure overload hypertrophy and heart failure.
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pubmed:affiliation |
Wihuri Research Institute, Helsinki, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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