Linked Life Data

12920491

Source:http://linkedlifedata.com/resource/pubmed/id/12920491

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
2003-9-23
pubmed:abstractText
The aims were to investigate: (1) The renal elimination of quinine and its metabolites 3-hydoxyquinine, 2'-quininone, (10R) and (10S)-11-dihydroxydihydroquinine and (2) the relative importance of CYP3A4, CYP1A2 and CYP2C19 for the formation of 2'-quininone, (10R) and (10S)-11-dihydroxydihydroquinine in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/10,11-dihydroxydihydroquinine, http://linkedlifedata.com/resource/pubmed/chemical/3-hydroxyquinidine, http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials, http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/Benzoquinones, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C19 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP1A2, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Fluvoxamine, http://linkedlifedata.com/resource/pubmed/chemical/Ketoconazole, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases, http://linkedlifedata.com/resource/pubmed/chemical/Quinidine, http://linkedlifedata.com/resource/pubmed/chemical/Quinine, http://linkedlifedata.com/resource/pubmed/chemical/Quinones, http://linkedlifedata.com/resource/pubmed/chemical/benzoquinone, http://linkedlifedata.com/resource/pubmed/chemical/quininone
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-6970
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
423-7
pubmed:dateRevised
2010-3-24
pubmed:meshHeading
pubmed-meshheading:12920491-Antimalarials, pubmed-meshheading:12920491-Area Under Curve, pubmed-meshheading:12920491-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:12920491-Benzoquinones, pubmed-meshheading:12920491-Chromatography, High Pressure Liquid, pubmed-meshheading:12920491-Cross-Over Studies, pubmed-meshheading:12920491-Cytochrome P-450 CYP1A2, pubmed-meshheading:12920491-Cytochrome P-450 CYP3A, pubmed-meshheading:12920491-Cytochrome P-450 Enzyme System, pubmed-meshheading:12920491-Drug Interactions, pubmed-meshheading:12920491-Fluvoxamine, pubmed-meshheading:12920491-Humans, pubmed-meshheading:12920491-Ketoconazole, pubmed-meshheading:12920491-Mixed Function Oxygenases, pubmed-meshheading:12920491-Quinidine, pubmed-meshheading:12920491-Quinine, pubmed-meshheading:12920491-Quinones, pubmed-meshheading:12920491-Time Factors
pubmed:year
2003
pubmed:articleTitle
Metabolism and elimination of quinine in healthy volunteers.
pubmed:affiliation
Department of Laboratory Medicine and Technology, C1-68 Huddinge University Hospital, 141 86 Stockholm, Sweden. rajaa.a.mirghani@labmed.ki.se
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't