|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3B
|
|
pubmed:dateCreated |
2003-8-4
|
|
pubmed:abstractText |
Previously we demonstrated that the antitumor efficacy of monoclonal antibodies against the EGFR (epidermal growth factor receptor) of human tumor xenografts mainly depends on the EGFR content of tumors rather than on the tumors' entity. In this study we wanted to elucidate whether the described cumulative effect of cisplatin and Anti-EGFR therapy also depends on the EGFR expression.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0250-7005
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2577-83
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:12894544-Adenocarcinoma,
pubmed-meshheading:12894544-Animals,
pubmed-meshheading:12894544-Antibodies, Monoclonal,
pubmed-meshheading:12894544-Antineoplastic Agents,
pubmed-meshheading:12894544-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12894544-Breast Neoplasms,
pubmed-meshheading:12894544-Carcinoma, Squamous Cell,
pubmed-meshheading:12894544-Cisplatin,
pubmed-meshheading:12894544-Combined Modality Therapy,
pubmed-meshheading:12894544-Drug Synergism,
pubmed-meshheading:12894544-Female,
pubmed-meshheading:12894544-Head and Neck Neoplasms,
pubmed-meshheading:12894544-Humans,
pubmed-meshheading:12894544-Mice,
pubmed-meshheading:12894544-Mice, Inbred BALB C,
pubmed-meshheading:12894544-Mice, Nude,
pubmed-meshheading:12894544-Receptor, Epidermal Growth Factor,
pubmed-meshheading:12894544-Tumor Cells, Cultured,
pubmed-meshheading:12894544-Uterine Cervical Neoplasms,
pubmed-meshheading:12894544-Xenograft Model Antitumor Assays
|
|
pubmed:articleTitle |
Carcinomas unresponsive to either cisplatinum or anti-EGFR therapy can be growth inhibited by combination therapy of both agents.
|
|
pubmed:affiliation |
Department of Otorhinolaryngology, University of Frankfurt, Medical School, 60590 Frankfurt/M., Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
