|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017953,
umls-concept:C0021311,
umls-concept:C0026336,
umls-concept:C0030956,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0038170,
umls-concept:C0205103,
umls-concept:C0332237,
umls-concept:C0332835,
umls-concept:C0355642,
umls-concept:C0443315,
umls-concept:C0445202,
umls-concept:C0536060,
umls-concept:C0596130,
umls-concept:C0677582,
umls-concept:C0683598,
umls-concept:C1522168,
umls-concept:C1553454
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2003-8-12
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|
pubmed:abstractText |
Bacteria that adhere to implanted medical devices play an important role in industry and in modern medicine. Staphylococci are among the most common pathogens that cause biomaterial infections. Vascular prosthetic graft infection is one of the most feared complications that the vascular surgeon treats, frequently resulting in prolonged hospitalization, organ failure, amputation, and death. A rat model was used to investigate the topical efficacies of temporin A and the quorum-sensing inhibitor RNAIII-inhibiting protein (RIP) as prophylactic agents of vascular prosthetic graft infections caused by Staphylococcus aureus and Staphylococcus epidermidis with intermediate resistance to glycopeptides.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
|
pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BalabanNaomiN,
pubmed-author:CirioniOscarO,
pubmed-author:D'AmatoGiuseppinaG,
pubmed-author:Dell'AcquaGiorgioG,
pubmed-author:GhiselliRobertoR,
pubmed-author:GiacomettiAndreaA,
pubmed-author:GovYaelY,
pubmed-author:KamyszWojciechW,
pubmed-author:LukasiakJerzyJ,
pubmed-author:MocchegianiFedericoF,
pubmed-author:OrlandoFiorenzaF,
pubmed-author:SabaVittorioV,
pubmed-author:ScaliseGiorgioG
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pubmed:issnType |
Electronic
|
|
pubmed:day |
12
|
|
pubmed:volume |
108
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
767-71
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12885754-Administration, Topical,
pubmed-meshheading:12885754-Animals,
pubmed-meshheading:12885754-Anti-Bacterial Agents,
pubmed-meshheading:12885754-Disease Models, Animal,
pubmed-meshheading:12885754-Dose-Response Relationship, Drug,
pubmed-meshheading:12885754-Drug Resistance, Microbial,
pubmed-meshheading:12885754-Drug Therapy, Combination,
pubmed-meshheading:12885754-Glycopeptides,
pubmed-meshheading:12885754-Implants, Experimental,
pubmed-meshheading:12885754-Male,
pubmed-meshheading:12885754-Microbial Sensitivity Tests,
pubmed-meshheading:12885754-Oligopeptides,
pubmed-meshheading:12885754-Polyethylene Terephthalates,
pubmed-meshheading:12885754-Proteins,
pubmed-meshheading:12885754-Rats,
pubmed-meshheading:12885754-Rats, Wistar,
pubmed-meshheading:12885754-Rifampin,
pubmed-meshheading:12885754-Staphylococcal Skin Infections,
pubmed-meshheading:12885754-Staphylococcus aureus,
pubmed-meshheading:12885754-Staphylococcus epidermidis,
pubmed-meshheading:12885754-Subcutaneous Tissue,
pubmed-meshheading:12885754-Treatment Outcome,
pubmed-meshheading:12885754-Vancomycin,
pubmed-meshheading:12885754-Vancomycin Resistance
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pubmed:year |
2003
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|
pubmed:articleTitle |
Prophylactic efficacy of topical temporin A and RNAIII-inhibiting peptide in a subcutaneous rat Pouch model of graft infection attributable to staphylococci with intermediate resistance to glycopeptides.
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pubmed:affiliation |
Institute of Infectious Diseases and Public Health, University of Ancona, Ancona, Italy.
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pubmed:publicationType |
Journal Article
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