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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2003-7-28
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pubmed:abstractText |
Increased stromal accumulation of macrophages and submucosal fibrosis due to excessive accumulation of collagens are central histologic features in ocular cicatricial pemphigoid (OCP). Interleukin (IL)-4 plays an important role in both the inflammatory and fibrotic events in several human and experimental diseases. In the present study, the possible role of IL-4 in the pathogenesis of OCP was investigated.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3417-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12882790-Collagen Type I,
pubmed-meshheading:12882790-Conjunctiva,
pubmed-meshheading:12882790-Conjunctival Diseases,
pubmed-meshheading:12882790-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12882790-Fibroblasts,
pubmed-meshheading:12882790-HSP47 Heat-Shock Proteins,
pubmed-meshheading:12882790-Heat-Shock Proteins,
pubmed-meshheading:12882790-Humans,
pubmed-meshheading:12882790-Immunoenzyme Techniques,
pubmed-meshheading:12882790-Interleukin-4,
pubmed-meshheading:12882790-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:12882790-Pemphigoid, Benign Mucous Membrane,
pubmed-meshheading:12882790-RNA, Messenger,
pubmed-meshheading:12882790-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2003
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pubmed:articleTitle |
Effects of IL-4 on conjunctival fibroblasts: possible role in ocular cicatricial pemphigoid.
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pubmed:affiliation |
Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA. razzaque_ahmed@hms.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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