Linked Life Data

1286205

Source:http://linkedlifedata.com/resource/pubmed/id/1286205

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-3-15
pubmed:abstractText
The relationship between the time course of cortical temperature (TCRT) and sleep-wake alternation was investigated by correlation analyses and a computer simulation. The data for these analyses were collected in 10 rats in a 4-day experiment (LD 12:12), during which vigilance states and TCRT were determined for consecutive 8-sec epochs. On day 1 baseline recordings were obtained; on day 2 the animals were sleep-deprived; and days 3 and 4 served as recovery days. The correlation analyses revealed that the alternation of sleep and waking accounted for 84% of the variance of TCRT when analyzed for hourly intervals. The residual variance displayed a 24-hr periodicity with an amplitude of 0.15 degrees C. Similar results were obtained in a separate data set of a 2-day experiment, which consisted of a baseline day (LD 12:12) and a day with constant darkness. The periodicity of the residual variance of TCRT can therefore be considered to represent the circadian temperature rhythm not masked by the vigilance states. In the computer simulation, the time course of TCRT was simulated on the basis of the sequence of the vigilance states with an 8-sec time resolution. It was assumed that TCRT increases during waking and rapid-eye-movement (REM) sleep according to an exponential saturating function, and decreases exponentially during non-REM sleep. The simulations could account for 88-93% of the variance of TCRT. We conclude that in the rat, the major part of the variation of TCRT is accounted for by vigilance states, whereas a minor part can be attributed to a direct effect of the circadian pacemaker.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0748-7304
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Sleep and waking have a major effect on the 24-hr rhythm of cortical temperature in the rat.
pubmed:affiliation
Institute of Pharmacology, University of Zürich, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't