Linked Life Data

12857996

Source:http://linkedlifedata.com/resource/pubmed/id/12857996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
2003-7-14
pubmed:abstractText
Inflammation is part of the response to infection. It is often considered to be part of the innate response to infection, but it plays a significant role in molding the adaptive response. Conserved pathways that have evolved to contain the infection and mold the ensuing adaptive response can cause deleterious effects when dysregulated. In this review, the various roles of TNFalpha will be discussed. Its pleomorphic effects require complex regulatory strategies. Our work has focused on the role of TNFalpha in autoimmune diseases and the regulation of its expression by transcription factors and chromatin remodeling.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0257-277X
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
529-38
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Regulation of inflammation.
pubmed:affiliation
Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. sullivak@mail.med.upenn.edu
pubmed:publicationType
Journal Article, Review