Linked Life Data

12848675

Source:http://linkedlifedata.com/resource/pubmed/id/12848675

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-7-9
pubmed:abstractText
Characterization of target organ damage from hypertension is of particular interest in African-Americans, and evidence from electrocardiographic studies suggests that left ventricular hypertrophy is a frequent clinical finding of considerable prognostic importance. Echocardiographic studies may permit more precise characterization of the pathologic impact of hypertension on cardiac structure and function. The objective of this study is to characterize left ventricular (LV) structure including measures of wall thickness, septal thickness, internal dimension, and mass in a middle-aged sample of African-Americans using echocardiography. This study is a cohort (cross-sectional) study in which 2445 middle-aged African-American study participants from a population-based sample initially enrolled by the Atherosclerosis Risk in Communities, Jackson, Mississippi Examination Center in 1987-1989 underwent an M-mode echocardiograpic examination at their third or fourth clinic visit in 1993-1996. Measures of LV mass, even where indexed by size were conspicuously greater in men compared to women, and men exhibited a demonstrably steeper gradient of LV mass across the rather restricted age range of the study. However, when gender specific thresholds for LV hypertrophy were utilized, African-American men appear to have lower prevalence of LV hypertrophy than women. The lowest prevalence of LV hypertrophy was observed in African-American men who did not have hypertension (28.4%). The findings confirm previous suggestions from electrocardiographic investigations that cardiac hypertrophy is common, if not epidemic in middle-aged African-American men and women, whether or not they have hypertension.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0742-2822
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-20
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:12848675-African Continental Ancestry Group, pubmed-meshheading:12848675-Arteriosclerosis, pubmed-meshheading:12848675-Chi-Square Distribution, pubmed-meshheading:12848675-Cohort Studies, pubmed-meshheading:12848675-Cross-Sectional Studies, pubmed-meshheading:12848675-Echocardiography, Doppler, pubmed-meshheading:12848675-Female, pubmed-meshheading:12848675-Humans, pubmed-meshheading:12848675-Hypertension, pubmed-meshheading:12848675-Hypertrophy, Left Ventricular, pubmed-meshheading:12848675-Incidence, pubmed-meshheading:12848675-Linear Models, pubmed-meshheading:12848675-Male, pubmed-meshheading:12848675-Middle Aged, pubmed-meshheading:12848675-Mississippi, pubmed-meshheading:12848675-Prognosis, pubmed-meshheading:12848675-Prospective Studies, pubmed-meshheading:12848675-Risk Assessment, pubmed-meshheading:12848675-Severity of Illness Index, pubmed-meshheading:12848675-Sex Distribution
pubmed:year
2003
pubmed:articleTitle
Echocardiographic left ventricular mass in African-Americans: the Jackson cohort of the Atherosclerosis Risk in Communities Study.
pubmed:affiliation
University of Mississippi Medical Center, Jackson, MS, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.