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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-7-8
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pubmed:abstractText |
We have produced hypertrophic and metaplastic changes of goblet cells in nasal epithelium of ovalbumin (OVA)-sensitized rats by intranasal challenge with OVA. A variety of allergic mediators and inflammatory cells are capable of stimulating goblet cell degranulation (epithelial mucus secretion); however, little is known about the mechanism by which antigen induces mucus hypersecretion.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0091-6749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-25
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:12847488-Animals,
pubmed-meshheading:12847488-Antigens,
pubmed-meshheading:12847488-Atropine,
pubmed-meshheading:12847488-Cell Degranulation,
pubmed-meshheading:12847488-Chromones,
pubmed-meshheading:12847488-Cimetidine,
pubmed-meshheading:12847488-Eosinophils,
pubmed-meshheading:12847488-Histamine,
pubmed-meshheading:12847488-Indomethacin,
pubmed-meshheading:12847488-Mucus,
pubmed-meshheading:12847488-Nasal Mucosa,
pubmed-meshheading:12847488-Neutrophils,
pubmed-meshheading:12847488-Ovalbumin,
pubmed-meshheading:12847488-Rats
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pubmed:year |
2003
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pubmed:articleTitle |
A mechanism of antigen-induced goblet cell degranulation in the nasal epithelium of sensitized rats.
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pubmed:affiliation |
Department of Otorhinolaryngology, Mie University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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