Linked Life Data

12831480

Source:http://linkedlifedata.com/resource/pubmed/id/12831480

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1434
pubmed:dateCreated
2003-6-30
pubmed:abstractText
Segregating hybrids often exhibit phenotypes that are extreme or novel relative to the parental lines. This phenomenon is referred to as transgressive segregation, and it provides a mechanism by which hybridization might contribute to adaptive evolution. Genetic studies indicate that transgressive segregation typically results from recombination between parental taxa that possess quantitative trait loci (QTLs) with antagonistic effects (i.e. QTLs with effects that are in the opposite direction to parental differences for those traits). To assess whether this genetic architecture is common, we tabulated the direction of allelic effects for 3252 QTLs from 749 traits and 96 studies. Most traits (63.6%) had at least one antagonistic QTL, indicating that the genetic substrate for transgressive segregation is common. Plants had significantly more antagonistic QTLs than animals, which agrees with previous reports that transgressive segregation is more common in plants than in animals. Likewise, antagonistic QTLs were more frequent in intra- than in interspecific crosses and in morphological than in physiological traits. These results indicate that transgressive segregation provides a general mechanism for the production of extreme phenotypes at both above and below the species level and testify to the possible creative part of hybridization in adaptive evolution and speciation.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-10583537, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-11092833, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-11298968, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-11528477, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-11606535, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-11607681, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-8100788, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-8844156, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-9071588, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-9262467, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-9584110, http://linkedlifedata.com/resource/pubmed/commentcorrection/12831480-9691061
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0962-8436
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
358
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1141-7
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
The genetic architecture necessary for transgressive segregation is common in both natural and domesticated populations.
pubmed:affiliation
Department of Biology, Indiana University, 1001 E. 3rd Street, Bloomington, IN 47405, USA. Iriesebe@indiana.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't