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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2003-6-24
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pubmed:abstractText |
Reversible neurotoxic symptoms were observed in three adult patients with absence status epilepticus on lamotrigine (LTG) therapy after administration of an IV bolus followed by oral valproic acid (VPA). Neurotoxicity was likely related to elevated serum LTG levels, as improvement correlated with discontinuing or reducing LTG dosage.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1991-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12821749-Administration, Oral,
pubmed-meshheading:12821749-Adult,
pubmed-meshheading:12821749-Ammonia,
pubmed-meshheading:12821749-Anticonvulsants,
pubmed-meshheading:12821749-Confusion,
pubmed-meshheading:12821749-Drug Interactions,
pubmed-meshheading:12821749-Drug Therapy, Combination,
pubmed-meshheading:12821749-Epilepsy, Absence,
pubmed-meshheading:12821749-Epilepsy, Generalized,
pubmed-meshheading:12821749-Female,
pubmed-meshheading:12821749-Glucuronosyltransferase,
pubmed-meshheading:12821749-Humans,
pubmed-meshheading:12821749-Injections, Intravenous,
pubmed-meshheading:12821749-Metabolic Detoxication, Drug,
pubmed-meshheading:12821749-Middle Aged,
pubmed-meshheading:12821749-Status Epilepticus,
pubmed-meshheading:12821749-Triazines,
pubmed-meshheading:12821749-Valproic Acid
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pubmed:year |
2003
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pubmed:articleTitle |
Neurotoxicity following addition of intravenous valproate to lamotrigine therapy.
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pubmed:affiliation |
Epilepsy Division, Department of Neurology, University of Alabama School of Medicine, Birmingham 35294, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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