Linked Life Data

12817470

Source:http://linkedlifedata.com/resource/pubmed/id/12817470

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-6-23
pubmed:abstractText
In order to enhance and target gene delivery we have previously established a novel method, termed magnetofection, which uses magnetic force acting on gene vectors that are associated with magnetic particles. Here we review the benefits, the mechanism and the potential of the method with regard to overcoming physical limitations to gene delivery. Magnetic particle chemistry and physics are discussed, followed by a detailed presentation of vector formulation and optimization work. While magnetofection does not necessarily improve the overall performance of any given standard gene transfer method in vitro, its major potential lies in the extraordinarily rapid and efficient transfection at low vector doses and the possibility of remotely controlled vector targeting in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1431-6730
pubmed:author
pubmed:issnType
Print
pubmed:volume
384
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
737-47
pubmed:dateRevised
2006-4-21
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
The magnetofection method: using magnetic force to enhance gene delivery.
pubmed:affiliation
Institute of Experimental Oncology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich, Germany.
pubmed:publicationType
Journal Article, Review