The nucleoside reverse transcriptase inhibitors used for the treatment of HIV-positive persons are now clearly associated with metabolic disorders. We determined the prevalence of and risk factors for hyperlactatemia in HIV-positive persons to assess the relevance of lactate venous blood concentrations during antiretroviral therapy.
Department of Biochemistry, Faculty of Medicine, University Hospital of Clermont-Ferrand, 28 Place Henri Dunant, BP. 38, 63000 Clermont-Ferrand, France.