Source:http://linkedlifedata.com/resource/pubmed/id/12781910
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-6-3
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pubmed:abstractText |
Human nerve growth factor (NGF) serum concentrations were measured in a healthy sample of 126 participants by a modified highly sensitive and specific two-site enzyme immunoassay. The measured NGF concentrations differ considerably from a normal distribution. The median NGF concentration was 19.68 pg/ml with an interquartile range of 11.06-41.74 pg/ml, which means that 50% of the NGF levels are in this range. In our healthy sample, we found no gender differences but a slight age-related decrease of NGF (r=-0.1326, P=0.1560). Moreover intraindividual stability of NGF was examined in ten volunteers, where no significant changes of serum NGF concentrations were detected over 4 weeks. This stability of our repetitive measurements over 4 weeks suggests that this neurotrophin may be an intraindividually solid marker at least in human serum.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
344
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12781910-Adult,
pubmed-meshheading:12781910-Age Factors,
pubmed-meshheading:12781910-Aged,
pubmed-meshheading:12781910-Female,
pubmed-meshheading:12781910-Humans,
pubmed-meshheading:12781910-Immunoenzyme Techniques,
pubmed-meshheading:12781910-Male,
pubmed-meshheading:12781910-Middle Aged,
pubmed-meshheading:12781910-Nerve Growth Factor,
pubmed-meshheading:12781910-Reference Values,
pubmed-meshheading:12781910-Sensitivity and Specificity,
pubmed-meshheading:12781910-Statistics, Nonparametric
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pubmed:year |
2003
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pubmed:articleTitle |
Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability.
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pubmed:affiliation |
Department of Psychiatry, Free University of Berlin, Eschenallee 3, 14050 Berlin, Germany. undine.lang@medizin.fu-berlin.de
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pubmed:publicationType |
Journal Article
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