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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-6-2
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pubmed:abstractText |
The authors previously reported that intratracheal delivery (ITD) of donor alloantigen induced donor-specific hyporesponsiveness to C57BL/10 cardiac allografts in CBA recipients and that blockade of the B7 pathways abrogated that hyporesponsiveness. In this study, the authors used a CD28-deficient model to evaluate which signal, either through CD28 or cytotoxic T-lymphocyte-associated antigen (CTLA4), is involved in the induction of hyporesponsiveness.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD28,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ctla4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoconjugates,
http://linkedlifedata.com/resource/pubmed/chemical/Isoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/abatacept
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1636-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12777848-Animals,
pubmed-meshheading:12777848-Antigens, CD,
pubmed-meshheading:12777848-Antigens, CD28,
pubmed-meshheading:12777848-Antigens, Differentiation,
pubmed-meshheading:12777848-CTLA-4 Antigen,
pubmed-meshheading:12777848-Cell Transplantation,
pubmed-meshheading:12777848-Graft Survival,
pubmed-meshheading:12777848-Heart Transplantation,
pubmed-meshheading:12777848-Immunoconjugates,
pubmed-meshheading:12777848-Isoantigens,
pubmed-meshheading:12777848-Male,
pubmed-meshheading:12777848-Mice,
pubmed-meshheading:12777848-Mice, Inbred C3H,
pubmed-meshheading:12777848-Mice, Inbred C57BL,
pubmed-meshheading:12777848-Spleen,
pubmed-meshheading:12777848-Time Factors,
pubmed-meshheading:12777848-Tissue Donors,
pubmed-meshheading:12777848-Trachea,
pubmed-meshheading:12777848-Transplantation Tolerance
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pubmed:year |
2003
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pubmed:articleTitle |
Role of the CTLA4 pathway in hyporesponsiveness induced by intratracheal delivery of alloantigen.
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pubmed:affiliation |
First Department of Surgery, Teikyo University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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