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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-5-29
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pubmed:abstractText |
Our previous studies showed that administration of dexamethasone plus food increased serum leptin levels 100% more than dexamethasone alone. We hypothesized that this increase in leptin from the meal could result directly from the provision of fuel metabolites rather than from the meal-induced rise in insulin. In the current study, we tested the effect of an i.v. lipid fuel source (Intralipid 20%/heparin) that would incur only a modest increase in insulin. This study was undertaken because the role of lipid in the regulation of human leptin levels has been controversial, with differing effects reported: stimulatory, inhibitory, or no effect at all.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10334310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10348493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10382582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10490795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10726909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10726911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10778861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-10868951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11016454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11022182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11231983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11244470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11246880,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11294689,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11600559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-11786596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-12039705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-1590379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-6138367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-8566229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-8784108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9002984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9153282,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9385619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9398728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9550541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9568685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9725642,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9768694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12773140-9801994
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
669-76
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12773140-Adult,
pubmed-meshheading:12773140-Anticoagulants,
pubmed-meshheading:12773140-Dexamethasone,
pubmed-meshheading:12773140-Drug Synergism,
pubmed-meshheading:12773140-Fasting,
pubmed-meshheading:12773140-Fat Emulsions, Intravenous,
pubmed-meshheading:12773140-Female,
pubmed-meshheading:12773140-Glucocorticoids,
pubmed-meshheading:12773140-Glucose,
pubmed-meshheading:12773140-Heparin,
pubmed-meshheading:12773140-Humans,
pubmed-meshheading:12773140-Hypoglycemic Agents,
pubmed-meshheading:12773140-Insulin,
pubmed-meshheading:12773140-Leptin,
pubmed-meshheading:12773140-Male
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pubmed:year |
2003
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pubmed:articleTitle |
Intralipid/heparin infusion suppresses serum leptin in humans.
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pubmed:affiliation |
Obesity Research Center, St Luke's/Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, NY 10025, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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