Linked Life Data

12743152

Source:http://linkedlifedata.com/resource/pubmed/id/12743152

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2003-5-13
pubmed:abstractText
The epidermal growth factor receptor (EGFR) is a mediator of squamous cell carcinoma of the head and neck (SCCHN) development. ZD1839 is an orally active, selective EGFR tyrosine kinase inhibitor. This phase II study sought to explore the activity, toxicity, and pharmacodynamics of ZD1839 in SCCHN.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0732-183X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1980-7
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:12743152-Administration, Oral, pubmed-meshheading:12743152-Adult, pubmed-meshheading:12743152-Aged, pubmed-meshheading:12743152-Aged, 80 and over, pubmed-meshheading:12743152-Antineoplastic Agents, pubmed-meshheading:12743152-Carcinoma, Squamous Cell, pubmed-meshheading:12743152-Disease-Free Survival, pubmed-meshheading:12743152-Female, pubmed-meshheading:12743152-Head and Neck Neoplasms, pubmed-meshheading:12743152-Humans, pubmed-meshheading:12743152-Illinois, pubmed-meshheading:12743152-Immunohistochemistry, pubmed-meshheading:12743152-Intubation, Gastrointestinal, pubmed-meshheading:12743152-Male, pubmed-meshheading:12743152-Middle Aged, pubmed-meshheading:12743152-Mitogen-Activated Protein Kinase 3, pubmed-meshheading:12743152-Mitogen-Activated Protein Kinases, pubmed-meshheading:12743152-Neoplasm Metastasis, pubmed-meshheading:12743152-Neoplasm Recurrence, Local, pubmed-meshheading:12743152-Quinazolines, pubmed-meshheading:12743152-Receptor, Epidermal Growth Factor, pubmed-meshheading:12743152-Survival Analysis, pubmed-meshheading:12743152-Treatment Outcome
pubmed:year
2003
pubmed:articleTitle
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck.
pubmed:affiliation
Section of Hematology/Oncology, Department of Medicine, University of Chicago, 5841 S Maryland Ave, MC 2115, Chicago, IL 60637-1470, USA. ecohen@medicine.bsd.uchicago.edu
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase II