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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-5-9
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pubmed:abstractText |
Chlamydia trachomatis heat shock protein 10 (Chsp10) is associated with chronic genital tract infection with C. trachomatis. Chsp10 is homologous to human chaperonin 10 (Cpn10) and early pregnancy factor (EPF), a form of human Cpn10 that is specifically secreted at the start of pregnancy. We investigated cross-reactions between serum anti-Chsp10 antibodies and anti-EPF antibodies in pregnant and nonpregnant patients. Pregnancy was found to be associated with the presence of anti-EPF antibodies, which are specifically induced in pregnant women with a history of C. trachomatis infection, and with the presence of serum anti-Chsp10 antibodies. We also found that infertility was associated with the presence of anti-Chsp10 and anti-EPF antibodies. The HLA class II haplotype DR8 DQ4 was associated with the presence of anti-Chsp10 antibodies but not of anti-EPF antibodies.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-10353888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-10496901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-10701835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-1357775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-1637966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-1886100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-1910687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-1970672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-2323098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-2600905,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-2853609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-313010,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-3330508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7585093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7590718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7679373,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7682817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7866655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7912672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-7914093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-8637592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-9114409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12738647-9666602
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Chaperonin 10,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ4 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Serological Subtypes,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR8 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Pregnancy Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Suppressor Factors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/early pregnancy factor
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1071-412X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
446-50
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12738647-Adolescent,
pubmed-meshheading:12738647-Adult,
pubmed-meshheading:12738647-Antibodies, Bacterial,
pubmed-meshheading:12738647-Antibody Formation,
pubmed-meshheading:12738647-Antigens, Bacterial,
pubmed-meshheading:12738647-Autoantibodies,
pubmed-meshheading:12738647-Chaperonin 10,
pubmed-meshheading:12738647-Chlamydia Infections,
pubmed-meshheading:12738647-Chlamydia trachomatis,
pubmed-meshheading:12738647-Cross Reactions,
pubmed-meshheading:12738647-Female,
pubmed-meshheading:12738647-HLA-DQ Antigens,
pubmed-meshheading:12738647-HLA-DR Antigens,
pubmed-meshheading:12738647-HLA-DR Serological Subtypes,
pubmed-meshheading:12738647-Haplotypes,
pubmed-meshheading:12738647-Humans,
pubmed-meshheading:12738647-Infertility, Female,
pubmed-meshheading:12738647-Male,
pubmed-meshheading:12738647-Peptides,
pubmed-meshheading:12738647-Pregnancy,
pubmed-meshheading:12738647-Pregnancy Proteins,
pubmed-meshheading:12738647-Suppressor Factors, Immunologic
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pubmed:year |
2003
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pubmed:articleTitle |
Cross-reactivity between Chlamydia trachomatis heat shock protein 10 and early pregnancy factor.
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pubmed:affiliation |
Biobanque de Picardie, 16 rue Fernel, 80000 Amiens, France. fay.betsou@biobanque-picardie.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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