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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-5-9
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pubmed:abstractText |
Extracellular uridine 5'-triphosphate (UTP) regulates a variety of biological functions in the airway epithelium, including chloride and fluid transport, mucociliary clearance and mucin secretion via the P2Y purinergic receptors. This study was undertaken to investigate which P2Y purinergic receptors are expressed in normal human middle ear epithelial (NHMEE) cells. We also determined the levels of mucin and lysozyme secretion and their mRNA expressions following stimulation with UTP in passage-2 cultured NHMEE cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0001-6489
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
362-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12737291-Cells, Cultured,
pubmed-meshheading:12737291-Ear, Middle,
pubmed-meshheading:12737291-Epithelial Cells,
pubmed-meshheading:12737291-Humans,
pubmed-meshheading:12737291-Immunoblotting,
pubmed-meshheading:12737291-Mucins,
pubmed-meshheading:12737291-Muramidase,
pubmed-meshheading:12737291-RNA, Messenger,
pubmed-meshheading:12737291-Receptors, Purinergic,
pubmed-meshheading:12737291-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12737291-Time Factors,
pubmed-meshheading:12737291-Uridine Triphosphate
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pubmed:year |
2003
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pubmed:articleTitle |
Effect of uridine 5'-triphosphate on mucin and lysozyme expression in human middle ear epithelial cells.
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pubmed:affiliation |
Department of Otorhinolaryngology, Yonsei University College of Medicine, Seodaemun-gu, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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