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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-5-6
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pubmed:abstractText |
A new generation of commercial animal PET cameras may accelerate drug development by streamlining preclinical testing in laboratory animals. However, little information on the feasibility of using these machines for quantitative PET in small animals is available. Here we investigate the reproducibility of microPET imaging of (11)C-raclopride in the rat brain and the effects of tracer-specific activity and photon scatter correction on measures of D2 receptor (D2R) availability.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
815-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12732684-Animals,
pubmed-meshheading:12732684-Carbon Radioisotopes,
pubmed-meshheading:12732684-Male,
pubmed-meshheading:12732684-Raclopride,
pubmed-meshheading:12732684-Rats,
pubmed-meshheading:12732684-Rats, Sprague-Dawley,
pubmed-meshheading:12732684-Receptors, Dopamine D2,
pubmed-meshheading:12732684-Reproducibility of Results,
pubmed-meshheading:12732684-Scattering, Radiation,
pubmed-meshheading:12732684-Tomography, Emission-Computed
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pubmed:year |
2003
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pubmed:articleTitle |
Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: effects of scatter correction and tracer specific activity.
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pubmed:affiliation |
Chemistry Department, Brookhaven National Laboratory, Upton, New York 11973-5000, USA. alexoff@bnl.gov
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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