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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5617
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pubmed:dateCreated |
2003-4-11
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pubmed:abstractText |
Glucose modulates many vital processes in photosynthetic plants. Analyses of Arabidopsis glucose insensitive2 (gin2) mutants define the physiological functions of a specific hexokinase (HXK1) in the plant glucose-signaling network. HXK1 coordinates intrinsic signals with extrinsic light intensity. HXK1 mutants lacking catalytic activity still support various signaling functions in gene expression, cell proliferation, root and inflorescence growth, and leaf expansion and senescence, thus demonstrating the uncoupling of glucose signaling from glucose metabolism. The gin2 mutants are also insensitive to auxin and hypersensitive to cytokinin. Plants use HXK as a glucose sensor to interrelate nutrient, light, and hormone signaling networks for controlling growth and development in response to the changing environment.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1-aminocyclopropane-1-carboxylic...,
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids, Cyclic,
http://linkedlifedata.com/resource/pubmed/chemical/Arabidopsis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokinins,
http://linkedlifedata.com/resource/pubmed/chemical/Ethylenes,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Hexokinase,
http://linkedlifedata.com/resource/pubmed/chemical/Indoleacetic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/ethylene,
http://linkedlifedata.com/resource/pubmed/chemical/indoleacetic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1095-9203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
300
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
332-6
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:12690200-Amino Acids, Cyclic,
pubmed-meshheading:12690200-Arabidopsis,
pubmed-meshheading:12690200-Arabidopsis Proteins,
pubmed-meshheading:12690200-Catalysis,
pubmed-meshheading:12690200-Cell Division,
pubmed-meshheading:12690200-Cytokinins,
pubmed-meshheading:12690200-Ethylenes,
pubmed-meshheading:12690200-Flowers,
pubmed-meshheading:12690200-Gene Expression,
pubmed-meshheading:12690200-Genes, Plant,
pubmed-meshheading:12690200-Glucose,
pubmed-meshheading:12690200-Hexokinase,
pubmed-meshheading:12690200-Indoleacetic Acids,
pubmed-meshheading:12690200-Light,
pubmed-meshheading:12690200-Mutagenesis,
pubmed-meshheading:12690200-Phosphorylation,
pubmed-meshheading:12690200-Plant Leaves,
pubmed-meshheading:12690200-Plant Roots,
pubmed-meshheading:12690200-Plants, Genetically Modified,
pubmed-meshheading:12690200-Signal Transduction
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pubmed:year |
2003
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pubmed:articleTitle |
Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling.
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pubmed:affiliation |
Department of Genetics, Harvard Medical School, and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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