Linked Life Data

12686759

Source:http://linkedlifedata.com/resource/pubmed/id/12686759

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-4-10
pubmed:abstractText
Aqueous extracts of Ginseng radix have traditionally been used in the treatment of diabetes mellitus. In the present study, the effect of Ginseng radix on c-Fos expression in the hippocampus of streptozotocin (STZ)-induced diabetic rats was investigated via immunohistochemistry. Decreased c-Fos expression in the CA regions of the hippocampus was observed in STZ-induced diabetes, and administration of Ginseng radix enhanced the STZ-induced inhibition of c-Fos expression both dose- and duration-dependently. These results suggest that hyperglycemia-induced suppression of Fos expression may trigger the diabetes-induced disruption of hippocampal information processing and that Ginseng radix may alleviate this diabetes-induced disturbance in hippocampal functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1347-8613
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Effect of ginseng radix on c-Fos expression in the hippocampus of streptozotocin-induced diabetic rats.
pubmed:affiliation
Department of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't