Source:http://linkedlifedata.com/resource/pubmed/id/12648942
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-3-21
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pubmed:abstractText |
Single-nucleotide polymorphisms (SNPs) in structural genes can have a dramatic effect on the biology of whole organisms, from bacteria and viruses to mammals. Here, we underscore the importance of SNPs in bacterial genes that contribute to the ability of pathogens to cause disease. SNPs that confer an adaptive advantage for bacterial pathogens have been discovered in the genes encoding the FimH and Dr adhesins of Escherichia coli and, most recently, Salmonella enterica sv. Typhimurium FimH.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0966-842X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-7
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pubmed:dateRevised |
2010-7-13
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pubmed:meshHeading |
pubmed-meshheading:12648942-Adhesins, Bacterial,
pubmed-meshheading:12648942-Adhesins, Escherichia coli,
pubmed-meshheading:12648942-Bacterial Adhesion,
pubmed-meshheading:12648942-Cell Line,
pubmed-meshheading:12648942-Escherichia coli,
pubmed-meshheading:12648942-Fimbriae Proteins,
pubmed-meshheading:12648942-Humans,
pubmed-meshheading:12648942-Polymorphism, Single Nucleotide,
pubmed-meshheading:12648942-Salmonella typhimurium,
pubmed-meshheading:12648942-Virulence
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pubmed:year |
2003
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pubmed:articleTitle |
Enterobacterial adhesins and the case for studying SNPs in bacteria.
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pubmed:affiliation |
Division of Infectious Disease, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98105, USA.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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