Linked Life Data

12644537

Source:http://linkedlifedata.com/resource/pubmed/id/12644537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2003-3-19
pubmed:abstractText
Interferon alpha (IFN-alpha) has antiangiogenic activity, although the underlying mechanism of action is unclear. Because human neuroendocrine (NE) tumors are highly vascularized and sensitive to IFN-alpha, we investigated whether the therapeutic effects of IFN-alpha result from an inhibition of angiogenesis mediated by a decrease in vascular endothelial growth factor (VEGF) gene expression.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Angiogenesis Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Endothelial Growth Factors, http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides..., http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha, http://linkedlifedata.com/resource/pubmed/chemical/Luciferases, http://linkedlifedata.com/resource/pubmed/chemical/Lymphokines, http://linkedlifedata.com/resource/pubmed/chemical/Pregnancy Proteins, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Vascular Endothelial..., http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factors, http://linkedlifedata.com/resource/pubmed/chemical/trophoblastic beta 1-glycoprotein...
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0027-8874
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
437-48
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:12644537-Angiogenesis Inhibitors, pubmed-meshheading:12644537-Animals, pubmed-meshheading:12644537-Antineoplastic Agents, pubmed-meshheading:12644537-Electrophoretic Mobility Shift Assay, pubmed-meshheading:12644537-Endothelial Growth Factors, pubmed-meshheading:12644537-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:12644537-Gene Expression Regulation, Neoplastic, pubmed-meshheading:12644537-Genes, Reporter, pubmed-meshheading:12644537-Immunohistochemistry, pubmed-meshheading:12644537-Intercellular Signaling Peptides and Proteins, pubmed-meshheading:12644537-Interferon-alpha, pubmed-meshheading:12644537-Luciferases, pubmed-meshheading:12644537-Lymphokines, pubmed-meshheading:12644537-Mice, pubmed-meshheading:12644537-Mice, Nude, pubmed-meshheading:12644537-Neovascularization, Pathologic, pubmed-meshheading:12644537-Neuroendocrine Tumors, pubmed-meshheading:12644537-Pregnancy Proteins, pubmed-meshheading:12644537-Promoter Regions, Genetic, pubmed-meshheading:12644537-RNA, Messenger, pubmed-meshheading:12644537-Receptors, Immunologic, pubmed-meshheading:12644537-Receptors, Vascular Endothelial Growth Factor, pubmed-meshheading:12644537-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:12644537-Time Factors, pubmed-meshheading:12644537-Transcription, Genetic, pubmed-meshheading:12644537-Transplantation, Heterologous, pubmed-meshheading:12644537-Tumor Cells, Cultured, pubmed-meshheading:12644537-Tumor Markers, Biological, pubmed-meshheading:12644537-Vascular Endothelial Growth Factor A, pubmed-meshheading:12644537-Vascular Endothelial Growth Factors
pubmed:year
2003
pubmed:articleTitle
Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis.
pubmed:affiliation
Department of Hepatology, Gastroenterology, Endocrinology and Metabolism, Charité, Campus Virchow-Klinikum, Humboldt-University, Berlin, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't