Source:http://linkedlifedata.com/resource/pubmed/id/12637110
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-3-14
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pubmed:abstractText |
Oral bisphosphonates are well established for the treatment and prevention of postmenopausal osteoporosis; however, they are poorly absorbed from the gastrointestinal (GI) tract and have been associated with GI adverse events. Thus, current dosing guidelines recommend that the patient not eat or lie down for at least 30 minutes after taking oral bisphosphonates, a requirement that is inconvenient and may be associated with reduced compliance. The drawbacks of these dosing requirements may be overcome either by reducing dosing frequency or by using alternative routes of administration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0149-2918
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-34
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12637110-Administration, Oral,
pubmed-meshheading:12637110-Biological Markers,
pubmed-meshheading:12637110-Bone Density,
pubmed-meshheading:12637110-Bone Resorption,
pubmed-meshheading:12637110-Clinical Trials, Phase II as Topic,
pubmed-meshheading:12637110-Diphosphonates,
pubmed-meshheading:12637110-Drug Administration Schedule,
pubmed-meshheading:12637110-Female,
pubmed-meshheading:12637110-Humans,
pubmed-meshheading:12637110-Injections, Intravenous,
pubmed-meshheading:12637110-Osteoporosis, Postmenopausal,
pubmed-meshheading:12637110-Time Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Effect of daily and intermittent use of ibandronate on bone mass and bone turnover in postmenopausal osteoporosis: a review of three phase II studies.
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pubmed:affiliation |
F. Hoffmann-La Roche Ltd., Pharmaceuticals Division, Basel, Switzerland. ralph.schimmer@roche.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Review
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