Linked Life Data

12634935

Source:http://linkedlifedata.com/resource/pubmed/id/12634935

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-3-13
pubmed:abstractText
Whole-body O(2) uptake ( VO(2)), O(2) deficit and the concentration of high-energy phosphates (determined by (31)P spectroscopy) in human calf muscle were measured during moderate aerobic square-wave exercise of increasing intensity in ten volunteers. Net VO(2) (above resting) increased linearly with mechanical power, yielding a delta efficiency of 13.1%. "Gross" O(2) deficit increased linearly with net VO(2). The fraction of phosphocreatine (PC) split at steady state increased linearly with the mechanical power and with the O(2) deficit. If the [PC] in resting muscle is known, the slope of the regression between PC split and O(2) deficit (in millimoles) yields the P/O(2) ratio. To calculate this, the O(2) deficit was corrected for the amount of O(2) derived from the body stores, as obtained from literature data. The value so obtained, for a resting [PC] of 30 mM was 5.9, consistent with canonical textbook values. Furthermore, the ratio of "true" O(2) deficit to steady-state VO(2) is a measure of the time constant of VO(2) kinetics at work onset at the muscle level: assuming a monoexponential time course without time delays it amounted to about 17 s, close to the value that can be expected in mammalian muscle at 37 degrees C.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
445
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
622-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Relationships between mechanical power, O(2) consumption, O(2) deficit and high-energy phosphates during calf exercise in humans.
pubmed:affiliation
Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi di Udine, P.le Kolbe 4, 33100, Udine, Italy. mfrancescato@mail.dstb.uniud.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't