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pubmed-article:12617908pubmed:abstractTextThis paper deals with the synthesis of a novel series of amphiphilic glycosylated spin-traps derived from alpha-Phenyl-N-tert-butyl nitrone (PBN) and an initial characterization of their anti-caspase-3 activity. Preliminary investigation of their anti-apoptosis effect showed they dramatically inhibit the activity of caspase-3 in cultured neuronal cells following induction of apoptosis by hydrogen peroxide.lld:pubmed
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pubmed-article:12617908pubmed:articleTitleSynthesis of a new family of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders.lld:pubmed
pubmed-article:12617908pubmed:affiliationLaboratoire de Chimie BioOrganique et des Systèmes Moléculaire Vectoriels, Faculté des Sciences, 33 rue Louis Pasteur, 84000 Avignon, France.lld:pubmed
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